Therapeutic
Intranasal Drug DeliveryInformational Links Related to Intranasal medication delivery
CONTACT INFORMATION for specific questions not addressed on this web site:
E-mail address - info@intranasal.net
(Be aware that we only check this e-mail during the times we update the site - about every 4 to 6 weeks. So if you are in a hurry you may be disappointed)
INTERNET DISCUSSIONS regarding IN therapy
Pain discussions
- Intranasal fentanyl relieves breakthrough cancer pain
- Intranasal fentanyl reduces pain due to pediatric long bone fractures
- German document on intranasal fentanyl for breakthrough pain and dyspnea
- Industry sponsored discussion of intranasal pain medications
- Intranasal fentanyl superior to oral transmucosal fentanyl for treatment of breakthrough pain in cancer patients
- Intranasal fentanyl in pediatric emergency rooms - Sally Britnell, RN presentation
- Intranasal fentanyl or intravenous morphine for analgesia in adults - Best Bets evidence based topic review.
- Intranasal Fentanyl versus parenteral opiates for acute pain in children - Best Bets evidence based topic review.
EMS links of interest
-
A Call for Widespread Application of Intranasal Medication Delivery
in the Prehospital Environment
- Australian Lay public education regarding treating seizures, calling 911 and using intranasal midazolam (PDF 0.2 MB)
- New South Wales EMS protocol for pediatric seizures (PDF 0.17 MB)
- Intranasal naloxone blog with Debra Kerr (researcher)
- Audio interview with Debra Kerr - IN naloxone researcher
- Project Lazarus - Home IN naloxone
- Legality of home naloxone - North Carolina
- Legality of home naloxone - Massachusetts
- Outpatient delivery of naloxone to reduce opioid overdose deaths
- San Diego county EMS protocol updates 2009 including discussion of nasal medication delivery
- Contra Costa EMS update 2010 (Intranasal naloxone pp 38-50)
- Intranasal fentanyl use in ski resort
- Inhaled methoxyflurane vs intranasal fentanyl for adult visceral pain in an ambulance
Hospice links of interest
- Palliative info web site by Mike Harlos, MD
- Lecture slides by Dr. Portenoy (Beth Isreal) regarding breakthrough Pain in hospice patients
- www.palliativedrugs.com
Sedation discussions
- Blog List serve discussion regarding intranasal Precedex (dexmedetomidine) for CT scanning in children
- Another very detailed link discussing IN Precedex for pediatric sedation in multiple settings in the hospital
- Discussion of a recent abstract that showed IN midazolam was superior to either buccal or oral midazolam
POSTED INTERNET ARTICLES (to go to peer reviewed articles for more PDF and web linked articles - click here)
Nose Brain Pathway articles
- Nosy neuroprotection - discussion of the nose brain pathway
- Hanson, IN drugs for neurodegenerative disorders, Policy Holder Advocate.pdf
Pain Articles
- Fitzgibbon, Nasal morphine for breakthrough pain, Pain 2003
- Industry sponsored articles in nasal pain medications
- British association for emergency medicine pediatric pain protocol (click here).
Seizure articles
- Lahat, IN midazolam vs IV diazepam for pediatric seizures, BMJ 2000
- Whitesell, IN midazolam vs rectal diazepam in status without an IV line - the evidence supports nasal midazolam, Abstract at NAPNP national conference 2009
- Ma, Clinical Guidelines on Management of Prolonged Seizures, HK J Paediatrics 2010
Intranasal Naloxone articles
- Kerr, IN verus IM naloxone for the treatment of heroin overdose, Addiction 2009
- Leavitt, Intranasal naloxone: Overcoming opiate overdose
- Wermeling, Opioid harm reduction strategies: focus on expanded access to intranasal naloxone. Pharmacotherapy 2010
Topical anesthetic articles
- A guidance for the use of topical anesthetics for nasal/oropharyngeal and laryngotracheal procedures
Pediatric reviews
INTRANASAL DRUG DELIVERY REVIEWS
- References for incident pain and incident dyspnea protocol
- Pires, Intranasal drug delivery - How, why, what for -extensive review, J Pharm Pharmaceut Sci 2009
- Naleen Bhandari, Intranasal medication delivery overview.ppt
INTERNET PROTOCOLS
- Intranasal diamorphine dosing table
- British association for emergency medicine pediatric pain protocol (click here).
- Palliative care incident pain and dyspnea protocol
- Sunshine Hospital emergency department pediatric IN fentanyl protocol
- Starship Children's hospital intranasal fentanyl protocol
- Princess Margaret Hospital educational information for parents after administration of IN fentanyl in the operating theatre
- Royal Children's Hospital Melbourne Australia intranasal pain treatment clinical practice guideline
Nasal Drug Compounding Pharmacies
Trusted Partner compounding pharmacy
Trusted partner compounding pharmacy PDF
Hospice links
Palliative care incident pain and dyspnea protocol
OTHER SITES OF INTEREST
- Everest ER (Medical care in extreme mountain environment - including IN medications due to difficulty with IV access and safety)
- World wide science organization listing of ongoing or recent research related to intranasal medication delivery of all types.